Question

What are the advantages offered by creating a mouse model with gene knockout?

Hint:

Make sure to remember that gene knockout models are important tools to study the effects of gene mutations, and are useful in disease biology.

Answer 1

Understanding Gene Function: Mouse models with gene knockout are beneficial for understanding the function of a specific gene. By eliminating a specific gene from the mouse genome, it is possible to observe the physiological or biological change that occurs in the mice. The changes, or lack thereof, give information regarding the function of the gene. Disease Modeling: Gene knockout models can simulate human genetic diseases. This helps researchers study the mechanism of disease progression, as well as help in developing new diagnostics and therapeutic methods. Searching for New Therapies: These models can be useful in testing new treatment approaches for human disease and to screen various therapies.