Question

The major product ‘P’ for the following sequence of reactions is :

• A.
• B.
• C.
• D.

Hint:

When solving reaction sequences:
   Analyze each reagent step-by-step and apply known reaction mechanisms.
   Clemmensen reduction (Zn/Hg, HCl) is used to reduce carbonyl groups to methylene (\(-\text{CH}_2-\)).
   LiAlH\(_4\) reduces amides to amines.

Answer 1

The Correct Option is D

1. First Step: Clemmensen Reduction (Zn/Hg, HCl): 
The Clemmensen reduction converts the ketone group (\(-\text{C}= \text{O}\)) into a methylene (\(-\text{CH}_2-\)) group.
Starting compound:
\[\text{Ph-CH}_2-\text{CO-CH}_2-\text{CH}_2-\text{NH}_2.\]
After Clemmensen reduction:
\[\text{Ph-CH}_2-\text{CH}_2-\text{CH}_2-\text{CH}_2-\text{NH}_2.\]
2. Second Step: LiAlH\(_4\) Reduction: 
LiAlH\(_4\) reduces amides (\(-\text{CONH}_2\)) to amines (\(-\text{CH}_2-\text{NH}_2\)). In this compound, no further reduction occurs as the ketone has already been reduced to \(-\text{CH}_2-\) in the first step.
3. Final Product: 
The major product (P) is:
\[\text{Ph-CH}_2-\text{CH}_2-\text{CH}_2-\text{CH}_2-\text{NH}_2.\]
Final Answer: \(\text{Ph-CH}_2-\text{CH}_2-\text{CH}_2-\text{CH}_2-\text{NH}_2\).