Question:
One which does not stabilize secondary and tertiary protein?
One which does not stabilize secondary and tertiary protein?
Updated On: Mar 21, 2025
H-H linkage
S-S linkage
- Vanderwoal’s force
- Hydrogen bonding
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Approach Solution - 1
Forces Stabilizing Protein Secondary and Tertiary Structures:
- Hydrogen Bonds: Formed between peptide bonds and side chain groups, stabilizing alpha helices and beta sheets.
- Disulfide Linkages (-S-S-): Covalent bonds formed between cysteine residues, providing structural stability to the protein.
- van der Waals Forces: Weak interactions between nonpolar side chains that help in folding and stability.
- Electrostatic Forces of Attraction: Ionic bonds between oppositely charged side chains (e.g., lysine and glutamate).
Exclusion:
Peroxide Linkages (-O-O-): These are not involved in stabilizing protein structures and do not contribute to secondary or tertiary structure stabilization.
Conclusion:
The secondary and tertiary structures of proteins are stabilized by hydrogen bonds, disulfide linkages, van der Waals forces, and electrostatic interactions. Peroxide linkages are not involved.
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The secondary and tertiary proteins are stabilized by hydrogen bonds, disulfide linkages, Van Dar Wall's, and electrostatic forces of attraction.
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Concepts Used:
Biomolecules
Biomolecules are the most essential organic molecules, which are involved in the maintenance and metabolic processes of living organisms. These non-living molecules are the actual foot-soldiers of the battle of sustenance of life.
There are four major classes of Biomolecules – Carbohydrates, Proteins, Nucleic acids and Lipids.
- Carbohydrates are chemically defined as polyhydroxy aldehydes or ketones or compounds which produce them on hydrolysis.
- Proteins are another class of indispensable biomolecules, which make up around 50per cent of the cellular dry weight. Proteins are polymers of amino acids arranged in the form of polypeptide chains. The structure of proteins is classified as primary, secondary, tertiary and quaternary in some cases.
- Nucleic acids refer to the genetic material found in the cell that carries all the hereditary information from parents to progeny. There are two types of nucleic acids namely, deoxyribonucleic acid (DNA) and ribonucleic acid (RNA). The main function of nucleic acid is the transfer of genetic information and synthesis of proteins by processes known as translation and transcription.
- Lipids are organic substances that are insoluble in water, soluble in organic solvents, are related to fatty acids and are utilized by the living cell.