Question:

Following representations P, Q, and R denote few steps of Griffith Experiment. Identify the correct one(s).
P. R strain → Inject into mice → Mice die
Q. S strain (Heat killed) → Inject into mice → Mice die
R. R strain → Inject into mice → Mice live

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Griffith’s experiment laid the foundation for the discovery of DNA as the genetic material.

Updated On: Apr 7, 2025
  • P only
  • R only
  • P and R
  • Q and R
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The Correct Option is B

Approach Solution - 1

Griffith's experiment demonstrated bacterial transformation. The correct representations are:

P. R strain → Inject into mice → Mice die - Incorrect: The non-virulent R strain alone cannot kill mice.

Q. S strain (Heat killed) → Injected into mice → Mice die - Incorrect: Heat-killed S strain alone cannot kill mice.

R. R strain → Inject into mice → Mice live - Correct: This was Griffith's control experiment showing R strain is non-lethal.

The correct answer is (B) R only, as this was the only completely accurate representation among the options given.

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Approach Solution -2

Griffith's experiment showed that bacteria can undergo transformation. The accurate representations are:

P. R strain → Inject into mice → Mice dieIncorrect: The harmless R strain alone does not kill mice.

Q. S strain (Heat-killed) → Inject into mice → Mice dieIncorrect: Heat-killed S strain alone is not lethal to mice.

R. R strain → Inject into mice → Mice liveCorrect: This was Griffith's control, proving the R strain is non-lethal.

The correct answer is (B) R only, as this was the only fully accurate option provided.

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