Question

Which of the following is true about Thalassemia?

• A. A
• B. B
• C. C
• D. D

Hint:

Thalassemia is a blood disorder caused by mutations in the genes for hemoglobin on chromosome 11.

Answer 1

The Correct Option is B

Step 1: Understanding the Question.
This question is asking about the chromosomal basis of Thalassemia, a genetic disorder.

Step 2: Analyzing the Options.
(A) Chromosome 16: This is incorrect, as Thalassemia is not caused by a mutation on chromosome 16.
(B) Chromosome 11: Correct — Thalassemia is caused by mutations in the genes for hemoglobin on chromosome 11.
(C) HbA1 and HbA2 are affected: This is partially correct but not specific enough, as the disorder specifically affects the genes for beta-globin on chromosome 11.
(D) Both (A) and (C): Incorrect, as (A) is wrong.

Step 3: Conclusion.
The correct answer is (B) Chromosome 11, as Thalassemia is linked to mutations in the genes located on chromosome 11.