Question:

Assertion (A): RNA is unstable and can mutate at a faster rate.
Reason (R): The presence of 2’-OH group in every nucleotide of RNA makes it labile and easily degradable.

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RNA Instability and Mutation Rate
Updated On: Feb 20, 2025
  • Both Assertion (A) and Reason (R) are true and Reason (R) is the correct explanation of the Assertion (A).
  • Both Assertion (A) and Reason (R) are true, but Reason (R) is not the correct explanation of the Assertion (A).
  • Assertion (A) is true, but Reason (R) is false.
  • Assertion (A) is false, but Reason (R) is true.
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The Correct Option is A

Solution and Explanation

Assertion (A): RNA is indeed more unstable compared to DNA due to the 2’-OH group in its sugar molecule, which makes it more prone to hydrolysis and degradation.
Reason (R): The presence of the 2’-OH group in RNA makes it more reactive, contributing to its instability and higher mutation rate
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