List of top Questions asked in GPAT

For disguishing the astringent and metallic taste of iron salts in children’s mixture, the following flavouring agent is used:

Match the following concept in List I with parameters in List II:

	List I Concept		List II Parameters
A	Volume of distribution	I	Measure volume of real physiological plasma
B	Evans blue	II	Human serum albumin
C	3.5-5%	III	Volume of blood
D	Metallothionin	IV	Ratioofbodydrug content to plasma concentration
	-	V	Protein present in kidney to bind metal

Choose the correct answer from the options give below:

Which of the following surfactants is an ANIONIC surfactant?

Clatharates crystallize in the form of

Which of the following ointment bases is an “absorption base”?

What is the percentage of alcohol in a mixture obtained by mixing 5 Lof 25%, 3 Lof 40% and 2Lof 15% alcohol?

A tablet excipient, whose function to ensure that table formulation and ejection can occur with low friction between the solid and the die wall is called:

Clear, sweetened hydroalcoholic solutions intended for oral use, usually flavoured to enhance their palatibility, are called:

The required amount of adjusting substance required to make a hypotonic solution, isotonic is given by the (where, W = adjusting substance, a = freezing point depression of unadjusted solution and b= freezing point depression of water)

Match the following List I with List II with respect to most specific Activity / Property in formulation of disperse system

	List I Formulation Ingredient		List II Activity / Property
	Salts of d-glu- curonic acid poly-peptides and amino acids		Are pseudoplastic and plastic in nature
	Surfactants, both ionic and non-ionic		Form a multimolecular film around the dispersed droplets of oil in an o/w emulsion
	Magnesium aluminium silicate		Emulsifier belonging to the class of solid particles forms w/o emulsions
	Structured vehicles		Emulsifier belonging to the class of solid particles and forms o/w emulsion
			Have been used to bring about flocculation of suspended particles

Choose the correct answer from the options given below:

The difference in velocity between two planes of liquids separated/infinitesimal distance is called

Which of the following Climatic Zones (as per WHO Criteria) refers to “hot and humid climate”?

Given below are two statements, one is labelled as Assertion A and other is labelled as ReasonR.
Assertion (A): Exotoxins diffuse freely through the bacterial call wall into the medium in which the organisms are growing. 
Reason (R): They are water soluble and can pass into the surrounding medium. 
In the light of the above statements, choose the correct answer from the options given below:

Match the process of reproduction and genetic exchange under Column I with the explanation under Column II. Match list-1 with List-II:

	List I Process of reproduction and genetic exchange		List II Explanation
A	Binary Fission	I	Transfer of genetic material from the donor recipient bacterium through cell contact
B	Transformation	II	Common vegetative reproduction
C	Transduction	III	Transfer of genetic material in bacteria through virus
D	Conjugation	IV	Horizontal gene transfer by taking up of foreign genetic material (naked DNA)

Which of the following is the common chemical name for Propellant 11?

Acrystalline powder that contains water of crystallization or hydration; this water can be liberated either during manipulations or an exposure to a low – humidity environment – then the powder will become sticky and pasty, or it may even liquefy. Such a powder is called:

Out of the following solvents which one is not a polar solvent?

A component of film-coating solution to make film more liable, enhance spread over tablets, beads and granules, is called:

Which of the following USP Glass Type is NOT SUITABLE for parenteral packaging?

Which of the following levels of IVIVC is represented by “the relatinship between one dissolution time point(e.g., t 50%) and one mean pharmacokinetic parameter, such as AUC, T_max or C_max”?

Under which of the following conditions in-vitro-in-vivo correlation for a drug fails?

Electrophilic substitution reaction of pyridine, when carried out in the presence of KNO₃ and conc. H2SO₄ at 300°C, leads to the formation of:

Kozeny carmen equation is used to determine the___.

In pharmacokinetic models, the term “compartment” means:

Which of the following emulsifiers has the highest HLB value?