Question

Which of the following transcription factors is said to be a master switch of the immune system, promoting cytokine expression during inflammation?

• A. Nuclear factor kappa B
• B. Transcription factor II
• C. DNA transcriptase
• D. RNA transcriptase

Hint:

NF-κB is essential for the immune system's response to inflammation and immune activation.

Answer 1

The Correct Option is A

Step 1: Understanding Nuclear Factor Kappa B (NF-κB) 
NF-κB is a transcription factor that plays a crucial role in regulating the immune response, including cytokine production during inflammation. 
Step 2: Evaluating the Options 
- Nuclear factor kappa B (NF-κB): Correct, it is a master switch for immune responses, activating various inflammatory genes. 
- Transcription factor II: A general transcription factor involved in transcription initiation but not specific to immune response. 
- DNA transcriptase: Not a transcription factor. 
- RNA transcriptase: Not a transcription factor either; it is related to RNA synthesis. 
Step 3: Conclusion 
NF-κB is the transcription factor responsible for cytokine expression during inflammation.