Question:

Which of the following substances, if introduce in the blood stream, would cause coagulation, at the site of its introduction ?

Updated On: Jul 13, 2024

Fibrinogen
Prothrombin
Heparin
Thromboplastin

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The Correct Option is D

Solution and Explanation

Lipoproteinaceous, thromboplastin is released by the injured tissue. This reacts with Ca++ ions present in blood and forms a proteinaceous enzyme called prothrombinase. Later in the presence of Ca++ inactivates heparin (anticoagulant) and catalyses prothrombin (inactive plasma protein) into an active thrombin protein. Thrombin acts as an enzyme and catalyses fibrinogen (a soluble plasma protein) into an insoluble fibre like polymer, fibrin. These fibres form a dense network upon the wound and trap blood corpuscles (WBCs, RBCs and platelets) and thus form a clot. This clot seals the wound and stop bleeding. In blood vessels, thromboplastin do not release due to which blood does not clot. But external thromboplastin to blood will cause blood clotting at the site of its introduction due to formation of prothrombinase.

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Immune System

It consists of tissues, cells, soluble molecules like antibodies and lymphoid organs. The WBC cells called the leucocytes have a significant role as they seek out to destroy the disease-causing organisms. These leucocytes are stored in different locations in the body including the spleen, bone marrow, and thymus. These organs are called as the lymphoid organs. The leucocytes are also present in the lymph nodes of the body.It is considered as the main lymphoid orga and. It produces all the blood cells including the lymphocytes. The thymus is an organ that is present near to the heart, beneath the breastbone.