Question:

Prostaglandins and leukotrienes are produced by:

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Mast cells release histamine, prostaglandins, and leukotrienes, which are essential mediators of inflammation, especially in allergic responses.
Updated On: May 6, 2025
  • B cells
  • Mast cells
  • Macrophages
  • NK cells
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The Correct Option is B

Solution and Explanation

Let's analyze each option:
(1) B cells: B cells are responsible for producing antibodies and are not involved in the production of prostaglandins or leukotrienes. Therefore, this is not the correct answer.
(2) Mast cells: Mast cells are a critical component of the immune response, especially in allergic reactions and inflammation. They produce prostaglandins and leukotrienes, which play a role in mediating these inflammatory processes. Hence, this is the correct answer.
(3) Macrophages: While macrophages are involved in producing inflammatory mediators, they are not the primary source of prostaglandins and leukotrienes. This is not the correct answer.
(4) NK cells (Natural Killer cells): NK cells are involved in killing infected and tumor cells but do not produce prostaglandins or leukotrienes. Hence, this is not the correct answer.
Conclusion: The correct answer is Option 2: Mast cells as they produce prostaglandins and leukotrienes during inflammatory responses.
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