The antigen binding sites are located in the Fab regions of the antibody. These regions are responsible for recognizing and binding to specific antigens.
(1) Fab regions of an antibody:
This is the correct answer. The antigen binding sites are found in the Fab regions of the antibody.
(2) Fc region of an antibody:
The Fc region is involved in immune system interactions but does not contain antigen binding sites. Hence, this is incorrect.
(3) Only in the light chain:
The light chain contributes to the Fab region, but antigen binding sites are not solely located in the light chain. Hence, this is incorrect.
(4) Only in the heavy chain:
Similar to the light chain, the heavy chain contributes to the Fab region, but antigen binding sites are not exclusively located in the heavy chain. Hence, this is incorrect.
Conclusion:
The correct answer is Option 1: Fab regions of an antibody as this is where the antigen binding sites are located.