Question

Which of the following statements are correct?
[I.] The packaging of chromatin at higher level requires additional set of proteins called non-histone chromosomal proteins.
[II.] In some viruses, the flow of genetic information for protein synthesis is in the reverse direction — that is from RNA to DNA.
[III.] RNA is the genetic material that is passed from virus to bacteria was given by Avery, Macleod and McCarty.
[IV.] RNA polymerase II transcribes the precursor of 5S RNA.

• A. I, II
• B. I, III
• C. III, IV
• D. I, IV

Hint:

Remember: - RNA polymerase I: rRNA (except 5S), - RNA polymerase II: mRNA, snRNA, etc., - RNA polymerase III: tRNA and 5S rRNA.

Answer 1

The Correct Option is A

Step 1: Analyze Statement I.
This is true. Chromatin packaging at higher levels involves non-histone chromosomal proteins along with histones to provide structural support and regulation. Step 2: Analyze Statement II.
This is true. In retroviruses (like HIV), reverse transcription occurs — genetic information flows from RNA to DNA. Step 3: Analyze Statement III.
This is false. The identification of DNA (not RNA) as the genetic material was demonstrated by Avery, MacLeod, and McCarty using Streptococcus pneumoniae. RNA is not the genetic material in this context. Step 4: Analyze Statement IV.
This is false. RNA polymerase III, not II, transcribes 5S rRNA. RNA polymerase II transcribes mRNA precursors.