Question:

What are passenger cells in transplantation?

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Passenger cells are the donor’s immune cells in the graft, playing a role in graft acceptance or rejection.
Updated On: Feb 10, 2025
  • Donor leukocytes in graft tissue
  • Recipient leukocytes around graft tissue
  • Recipient dendric cells
  • Recipient T cells
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The Correct Option is A

Solution and Explanation

Step 1: Understanding Passenger Cells 
Passenger cells refer to the donor’s immune cells (leukocytes) present in the transplanted tissue, which can influence the recipient’s immune response. 
Step 2: Evaluating the Options 
- Donor leukocytes in graft tissue: Correct, these cells can affect the immune rejection process in the recipient. 
- Recipient leukocytes around graft tissue: Incorrect, these are not considered passenger cells. 
- Recipient dendric cells: Incorrect, these are not specifically passenger cells. 
- Recipient T cells: Incorrect, they are part of the recipient's immune system. 
Step 3: Conclusion 
Passenger cells are donor leukocytes within the graft tissue.

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