Step 1: Using the exponential decay formula.
The exponential decay formula is given by:
\[
A(t) = A_0 e^{-kt}
\]
where \( A_0 \) is the initial amount, \( k \) is the decay constant, and \( t \) is the time.
Step 2: Applying the given information.
Initially, there are 27 grams of the substance, so \( A_0 = 27 \). After 3 hours, 8 grams are left. Using the formula:
\[
8 = 27 e^{-3k}
\]
Solving for \( k \), we get:
\[
e^{-3k} = \frac{8}{27}, \quad -3k = \ln \left( \frac{8}{27} \right), \quad k = \frac{-\ln \left( \frac{8}{27} \right)}{3}
\]
Step 3: Finding the amount left after 4 hours.
Now, we substitute \( k \) into the equation for \( A(t) \) to find the amount left after 4 hours:
\[
A(4) = 27 e^{-4k}
\]
After calculating this, we find that \( A(4) = \frac{16}{3} \) grams.
Step 4: Conclusion.
Thus, the amount left after 4 hours is \( \frac{16}{3} \) grams, which makes option (D) the correct answer.