Question

The major products for the following reaction is

• A.
• B.
• C.
• D.

Answer 1

The Correct Option is B

The reaction involves the interaction of a nucleophile (\( \text{HS-} \)) with an electrophilic site on the given substrate. - \( \text{SH} \) is a better nucleophile than \( \text{OH} \) due to the softness of sulfur compared to oxygen. - Soft nucleophiles prefer to attack soft electrophilic centers, following the principle of hard-soft acid-base (HSAB) theory. The mechanism proceeds as follows: 1. The sulfur atom in \( \text{SH} \) attacks the electrophilic carbon of the \( \text{C=N} \) group. 2. This leads to the formation of a new bond between sulfur and carbon. 3. The \( \text{OH} \) group remains intact as sulfur is the more reactive nucleophile in this scenario. The major product of the reaction is: \[ \text{HO-CH(SH)-CN}. \] Thus, the correct product matches option (2).