Plasmodium falciparum is the deadliest malaria parasite due to its ability to cause severe complications. Other species like vivax and malariae are less aggressive.
Definition of Malignant Malaria: Malignant malaria, or severe malaria, is a life-threatening form of the disease characterized by complications like cerebral malaria and organ failure.
Option Analysis:
(1) Plasmodium falciparum: This parasite is known to cause severe malaria, leading to high mortality if untreated. It is the primary cause of malignant malaria.
(2) Plasmodium rubrum: This is not a recognized species of Plasmodium. It is incorrect.
(3) Plasmodium malariae: Causes a milder form of malaria with quartan fever, not severe or malignant malaria. This is incorrect.
(4) Plasmodium vivax: Causes relapsing malaria, which is generally less severe than falciparum malaria. This is incorrect.
Pathophysiology Insight: Plasmodium falciparum infects red blood cells, leading to their adhesion to blood vessel walls, causing blockages and severe symptoms. This distinguishes it from other species.
Conclusion: The correct answer is (1) Plasmodium falciparum, as it is the only species associated with malignant malaria.