If the sequence of the coding strand in a transcription unit is written as follows:
5-ATGCATGCATGCATGCATGCATGCATGC-3
Write down the sequence of mRNA.
If the sequence of the coding strand in a transcription unit is written as follows:
5-ATGCATGCATGCATGCATGCATGCATGC-3
Write down the sequence of mRNA.
Solution and Explanation
If the coding strand in a transcription unit is
5− ATGCATGCATGCATGCATGCATGCATGC-3
Then, the template strand in 3 to 5 direction would be
3− TACGTACGTACGTACGTACGTACGTACG-5
It is known that the sequence of mRNA is same as the coding strand of DNA.
However, in RNA, thymine is replaced by uracil.
Hence, the sequence of mRNA will be
5 − AUGCAUGCAUGCAUGCAUGCAUGCAUGC-3
Top Questions on Molecular Basis of Inheritance
- Distance between two consecutive base pairs of DNA is \rule{2cm}{0.1mm}
- CBSE Compartment XII - 2025
- Biology
- Molecular Basis of Inheritance
- The flows of genetic information in central dogma are in which direction?
- CBSE Compartment XII - 2025
- Biology
- Molecular Basis of Inheritance
- Which one of the following codons has dual function?
- CBSE Compartment XII - 2025
- Biology
- Molecular Basis of Inheritance
- Study the items of Column-I and those of Column-II:
Column-I Column-II
(a) RNA polymerase I (i) 18s rRNA
(b) RNA polymerase II (ii) SnRNAs
(c) RNA polymerase III (iii) hnRNA
Choose the option that correctly matches the items of Column-I with those of Column-II:- CBSE CLASS XII - 2025
- Biology
- Molecular Basis of Inheritance
- The RNA triplet UAG acts as a stop codon which terminates the synthesis of a polypeptide. Below is given a strand of DNA which codes for four amino acids.
In which position will an insertion of a thymine nucleotide result in the termination of translation?
DNA strand:
3′ T C C A C C C G A T G C 5′- CBSE CLASS XII - 2025
- Biology
- Molecular Basis of Inheritance
Questions Asked in CBSE CLASS XII exam
Bittu and Chintu were partners in a firm sharing profit and losses in the ratio of 4 : 3. Their Balance Sheet as at 31st March, 2024 was as follows:
On 1st April, 2024, Diya was admitted in the firm for \( \frac{1}{7} \)th share in the profits on the following terms:- (i) New profit sharing ratio between Bittu, Chintu and Diya was 3 : 3 : 1 .
- (ii) Fixed Assets were found to be overvalued by ₹ 1,40,000.
- (iii) Creditors were paid ₹ 4,20,000 in full settlement.
- (iv) Diya brought proportionate capital and ₹ 5,60,000 as her share of goodwill premium by cheque.
Prepare Revaluation Account and Partners' Capital Accounts.
- CBSE CLASS XII - 2025
- Partnership Accounts
- Pass the necessary journal entries for the following transactions on the dissolution of a partnership firm of Vibha and Ajit after various assets (other than cash) and external liabilities have been transferred to Realisation Account:}
Creditors worth ₹ 46,000 accepted ₹ 9,000 cash and furniture of ₹ 32,000 in full settlement of their claim.
The firm had stock of ₹ 20,000. Ajit took over 40% of the stock at a discount of 10% while the remaining stock was sold for ₹ 18,000.
Vibha was appointed to look after dissolution work for which she was allowed a remuneration of ₹ 16,000. Vibha agreed to bear the dissolution expenses. Actual dissolution expenses ₹ 15,000 were paid by Vibha.
Ajit’s loan of ₹ 45,000 was settled at ₹ 42,000.
A machine which was not recorded in the books was taken over by Vibha at ₹ 23,000, whereas its expected value was ₹ 28,000.
The firm had a debit balance of ₹ 20,000 in the Profit and Loss Account on the date of dissolution.- CBSE CLASS XII - 2025
- Dissolution of Partnership Firms
- How does the process of Natural Selection affect Hardy-Weinberg equilibrium? Explain with the help of graphs.
- CBSE CLASS XII - 2025
- evolution
- A battery of emf \( E \) and internal resistance \( r \) is connected to a rheostat. When a current of 2A is drawn from the battery, the potential difference across the rheostat is 5V. The potential difference becomes 4V when a current of 4A is drawn from the battery. Calculate the value of \( E \) and \( r \).
- CBSE CLASS XII - 2025
- Current electricity
- An electric dipole of dipole moment \( 1.0 \times 10^{-12} \ \text{Cm} \) lies along the x-axis. An electric field of magnitude \( 2.0 \times 10^4 \ \text{NC}^{-1} \) is switched on at an instant in the region. The unit vector along the electric field is \( \frac{\sqrt{3}}{2} \hat{i} + \frac{1}{2} \hat{j} \). The magnitude of the torque acting on the dipole at that instant is:
Concepts Used:
Transcription
The very first stage of gene expression is the procedure of transcription. In this procedure, mRNA is the place where the genetic information is stored which later aids in encoding a protein. In this process, the DNA strand acts as a guide in the making of mRNA. Despite the fact that there is one exception which is adenine base pairs with uracil instead of thymine.
Transcription Unit:
The transcription unit is a set of freshly combined RNA molecules that have been transcribed from DNA. The cause is to encode at least one gene. A protein that has been encoded or encrypted with a DNA transcription unit may have a coding sequence. Transcription has a lower copying fidelity rate when differentiated from DNA replication.
The Stages of Transcription:
The procedure of transcription is enzymatically catalyzed into three steps:
- Initiation
- Elongation
- Termination