Question:

The base sequence in one of the strands of DNA is: ‘TAGCATGAT’
  • Give the base sequence of its complementary strand.
  • How are these base pairs held together in DNA molecule?
  • Explain the base complementarity rule. Name the scientist who framed this rule.

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A–T have 2 hydrogen bonds, C–G have 3. Chargaff's rule explains DNA base pairing.
Updated On: Jun 20, 2025
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Solution and Explanation

  1. The complementary strand of TAGCATGAT is: ATCGTACTA
  2. These base pairs are held together by hydrogen bonds — adenine (A) pairs with thymine (T) via 2 hydrogen bonds, and cytosine (C) pairs with guanine (G) via 3 hydrogen bonds.
  3. The base complementarity rule states that A pairs with T and C pairs with G in DNA. This rule was framed by the scientist Erwin Chargaff.
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