Step 1: Recall Intermediate Value Theorem.
A continuous function crossing zero between \(x_1\) and \(x_2\) must take opposite signs at the endpoints.
Step 2: Use monotonicity.
If \(f(x)\) is monotonic, then there can be at most one crossing. Given there is exactly one root, the sign at \(x_1\) and \(x_2\) must differ.
Step 3: Mathematical condition.
\[
f(x_1)\cdot f(x_2) < 0.
\]
Step 4: Eliminate wrong options.
- (A) Same sign → no root. Contradiction.
- (B) Product zero → would mean root lies at endpoint, but problem states root in \((x_1, x_2)\).
- (D) Equality of values → contradicts monotonicity unless constant (which would not give one root).
Final Answer:
\[
\boxed{f(x_1)f(x_2) < 0}
\]
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