To solve this problem, we need to identify the incorrect statements regarding blood groups based on the options provided.
1. Understanding the Statements:
Let's evaluate each statement:
- Statement I: "The mother with Rh- blood group develops passive immunity on administering IgM antibodies." - This statement is incorrect. Rh- mothers are at risk of Rh incompatibility with their Rh+ fetus, and passive immunity would not be conferred through IgM antibodies. Instead, IgG antibodies are involved in Rh incompatibility, not IgM. This makes the statement incorrect.
- Statement II: "Isoagglutinogens are sugar polymers bound to fatty acids on the RBC membrane." - This statement is correct. Isoagglutinogens are specific antigens (like A and B antigens) found on the surface of red blood cells (RBCs), which are made up of sugar polymers bound to lipid molecules.
- Statement III: "The alleles for Rh factor are located on three different loci on chromosome pair 9." - This statement is incorrect. The alleles for the Rh factor (like Rh+ and Rh-) are located at a single locus on chromosome 9, not three different loci. Therefore, this statement is incorrect.
- Statement IV: "The expression of ABO blood types in man is by three alleles of a single gene." - This statement is correct. The ABO blood group system is determined by three alleles (A, B, and O) of a single gene located on chromosome 9.
2. Conclusion:
Based on the analysis, the incorrect statements are Statements I and III.
Final Answer:
The correct answer is Option C: I, III.