Identify the incorrect statements regarding blood groups:
Statements:
(1) The mother with Rh\(^{-}\) blood group develops passive immunity on administering IgM antibodies.
(2) Isoagglutinogens are sugar polymers bound to fatty acids on the RBC membrane.
(3) The alleles for Rh factor are located on three different loci on chromosome pair 9.
(4) The expression of ABO blood types in man is by three alleles of a single gene.
Identify the incorrect statements regarding blood groups:
Statements:
(1) The mother with Rh\(^{-}\) blood group develops passive immunity on administering IgM antibodies.
(2) Isoagglutinogens are sugar polymers bound to fatty acids on the RBC membrane.
(3) The alleles for Rh factor are located on three different loci on chromosome pair 9.
(4) The expression of ABO blood types in man is by three alleles of a single gene.
Show Hint
- II, IV
- I, II
- I, III
- II, III
The Correct Option is C
Solution and Explanation
To solve this problem, we need to identify the incorrect statements regarding blood groups based on the options provided.
1. Understanding the Statements:
Let's evaluate each statement:
- Statement I: "The mother with Rh- blood group develops passive immunity on administering IgM antibodies." - This statement is incorrect. Rh- mothers are at risk of Rh incompatibility with their Rh+ fetus, and passive immunity would not be conferred through IgM antibodies. Instead, IgG antibodies are involved in Rh incompatibility, not IgM. This makes the statement incorrect.
- Statement II: "Isoagglutinogens are sugar polymers bound to fatty acids on the RBC membrane." - This statement is correct. Isoagglutinogens are specific antigens (like A and B antigens) found on the surface of red blood cells (RBCs), which are made up of sugar polymers bound to lipid molecules.
- Statement III: "The alleles for Rh factor are located on three different loci on chromosome pair 9." - This statement is incorrect. The alleles for the Rh factor (like Rh+ and Rh-) are located at a single locus on chromosome 9, not three different loci. Therefore, this statement is incorrect.
- Statement IV: "The expression of ABO blood types in man is by three alleles of a single gene." - This statement is correct. The ABO blood group system is determined by three alleles (A, B, and O) of a single gene located on chromosome 9.
2. Conclusion:
Based on the analysis, the incorrect statements are Statements I and III.
Final Answer:
The correct answer is Option C: I, III.
Top Questions on Genetics
- With the help of the given pedigree, find out the probability for the birth of a child having no disease and being a carrier (has the disease mutation in one allele of the gene) in the F3 generation.
- Consider the following statements:
Assertion (A): In human beings, Y-linked genes of non-homologous part are called holandric genes
Reason (R): Y-chromosome is present in males only - If a gene has four alleles, possible number of genotypes are
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II. Sickle cell anaemia is caused by a point mutation where valine at 6th position is replaced by glutamic acid
III. Protonopia is red colour blindness
IV. Phenyl ketonuria is an allosomal metabolic genetic disorder
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