Question:

Identify correct statements regarding the Human Genome Project: 
Statements :
I. The method of DNA sequencing was developed by Jeffreys.
II. Identification of genes that express as RNA is referred to as Expressed Sequence Annotation.
III. About 1.4 million locations where single base DNA differences occur in humans.
IV. Y-chromosome has 231 genes.

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The Human Genome Project's discoveries continue to influence a wide range of scientific and medical fields.
Updated On: Apr 15, 2025
  • I, III
  • II, IV
  • III, IV
  • II, III
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The Correct Option is C

Solution and Explanation

To solve the problem, we need to identify the correct statements regarding the Human Genome Project.

1. Analyzing the Statements:

Statement I: "The method of DNA sequencing was developed by Jeffreys." This statement is incorrect. DNA sequencing, as we know it today, was primarily developed by Frederick Sanger, not Jeffreys.

Statement II: "Identification of genes that express as RNA is referred to as Expressed Sequence Annotation." This statement is correct. The process involves identifying genes that are actively transcribed into RNA and annotating their sequences.

Statement III: "About 1.4 million locations where single base DNA differences occur in humans." This statement is correct. The Human Genome Project identified many single nucleotide polymorphisms (SNPs) that occur across human genomes.

Statement IV: "Y-chromosome has 231 genes." This statement is correct. The Y-chromosome is known to contain around 231 functional genes.

2. Analyzing the Correct Combination:
The correct statements are III and IV.

Final Answer:
The correct option is (C) III, IV.

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