Biologically active adrenaline and ephedrine used to increase blood pressure contain :
- Primary amino group
- Secondary amino group
- Tertiary amino group
- Quaternary ammonium salt
The Correct Option is B
Approach Solution - 1
- Adrenaline and ephedrine are both sympathomimetic amines that act on the sympathetic nervous system, primarily used to increase blood pressure.
- These compounds both contain a secondary amino group, which means the nitrogen atom is bonded to two carbon atoms (part of an alkyl or aryl group) and one hydrogen atom.
- The secondary amino group is critical for their biological activity, as it plays a key role in interacting with receptors that regulate blood pressure.
Thus, the correct answer is (B) Secondary amino group.
Approach Solution -2
Both adrenaline (epinephrine) and ephedrine have a secondary amino group in their structure, which is crucial for their biological activity in stimulating the central nervous system and increasing blood pressure.
Top Questions on Amines
For the reaction sequence given below, the correct statement(s) is(are):
Amines have a lone pair of electrons on the nitrogen atom, due to which they behave as Lewis bases. Greater the value of \( K_b \) or smaller the value of \( pK_b \), stronger is the base. Amines are more basic than alcohols, ethers, esters, etc. The basic character of aliphatic amines should increase with the increase of alkyl substitution. However, it does not occur in a regular manner, as a secondary aliphatic amine is unexpectedly more basic than a tertiary amine in aqueous solutions. Aromatic amines are weaker bases than ammonia and aliphatic amines. Electron-releasing groups such as \( -CH_3 \), \( -NH_2 \), etc., increase the basicity, while electron-withdrawing substituents such as \( -NO_2 \), \( -CN \), halogens, etc., decrease the basicity of amines. The effect of these substituents is more pronounced at the para-position than at the meta-position.
Arrange the following in increasing order of their basic character. Give reason:
- Give plausible explanation for each of the following:
Amides are less basic than amines. - Give plausible explanation for each of the following:
Aromatic primary amines cannot be prepared by Gabriel Phthalimide synthesis. - Arrange the following compounds in increasing order of their boiling point:
\[ \text{(CH}_3\text{)}_2\text{NH, CH}_3\text{CH}_2\text{NH}_2, \text{CH}_3\text{CH}_2\text{OH} \]
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