Question

(a) Write the product obtained when D-glucose reacts with \( H_2N - OH \).

Hint:

Hydroxylamine reacts with aldehydes and ketones to produce oximes, which serve as valuable intermediates in organic synthesis.

Answer 1

When D-glucose reacts with hydroxylamine (\( H_2N - OH \)), it forms an oxime. The aldehyde group of D-glucose reacts with hydroxylamine, resulting in the formation of a stable oxime with the general structure \( R - C = N - OH \), where R represents the rest of the glucose molecule. In this reaction, the glucose aldehyde undergoes a nucleophilic addition to yield the corresponding oxime. \bigskip