A population is in genetic equilibrium/Hardy-Weinberg equilibrium for a gene with 2 alleles (dominant allele is ‘A’ and recessive allele ‘a’). If the frequency of allele ‘A’ is 0.6, then the frequency of genotype ‘Aa’ is:
According to Hardy-Weinberg equilibrium, the frequency of heterozygotes (Aa) is given by 2pq, where: - p is the frequency of allele A (p = 0.6) - q is the frequency of allele a (q = 1−p=0.4) The frequency of genotype Aa is: 2pq = 2(0.6)(0.4) = 0.48