List of top Clinical Pharmacy and Therapeutics Questions asked in GPAT

Name the following drug molecule:

Anti-rheumatoid drug which is contraindicated in patients with renal and hepatic impairment

Which of the following drugs does not bind to haemoglobin?
A. Chlorpromazine
B. Phenobarbital
C. Phenothizine
D. Phenytoin
Choose the most appropriate answer from the options given below:

When a New Drug Application (NDA) made?

Which of the statement is true in geriatrics practice?

Match List I with List II

	List I-Mechanism of action		List II-Drugs
A	DPP4 inhibitors	I	Metformin
B	KATP Channel blocker	II	Pioglitazone
C	PPAR activator	III	Glimepiride
D	AMP Activator	IV	Teneligliptin
E	-	V	α glucosidase inhibitors

Choose the correct answer from the options given below:

Match List I with List II

	List I		List II
A	Phase‐I	I	Post marketing surveillance
B	Phase‐0	II	Micro dosing
C	Phase‐3	III	First in human dose
D	Phase‐4	IV	Multicentric trials

Choose the correct answer from the options given below:

A neonate suffering from icterus is intravenously administered with phenobarbital. The justification for this therapy is:

Which of the following could be the reason(s) for Pharmacokinetic Drug Interactions?
A. Interference with absorption 
B. Changes in protein binding 
C. Competition at receptor sites 
D. Interference with renal excretion 
Choose the correct answer from the options given below:

Which of the following is wrongly matched combination of anti-arrhythmic drugs and their class?

Which among the following statement is correct with respect to their mechanism of action?

A hypertensive patient Mr. Zee already receiving a drug 'X' to control his blood pressure was prescribed a tricyclic antidepressant. This resulted in the abolition of the antihypertensive action of 'X'. Which of the following drug could be 'X'.

To monitor the safety of the new drug under actual conditions of use in large number of patients has been classified as____ clinical trials.

Distribution is perfusion rate limited in case of ......drugs

The majority of drugs that least binded to antivascular tissue is

Some individuals are obsessed with using purgatives regularly as a reflection of their psychological problem. Dangers of purgative overuse include all of the following EXCEPT:

Identify phase of clinical trial having following features:
(A) Trial is conducted on about 3000 patients
(B) Purpose of trial is therapeutic confirmation
(C) Safety and tolerability is evaluated on wider scale
(D) Completion of trial is followed by New Drug Application (NDA)

When two brands of a drug product gives same clinical results, it is termed as :

Following are the facts regarding clinical applications of muscarinic receptor blocking drugs. Identify the false statement:

The following combination of drugs are used in treating severe travelers diarrhoea :