Question

Which of the following drugs does not bind to haemoglobin?
A. Chlorpromazine
B. Phenobarbital
C. Phenothizine
D. Phenytoin
Choose the most appropriate answer from the options given below:

• A. B, C and D only
• B. B and D only
• C. C and D only
• D. A only

Answer 1

The Correct Option is A

To determine which drugs do not bind to haemoglobin, we need to examine the properties of each drug mentioned:

1. Chlorpromazine: Chlorpromazine is a typical antipsychotic drug used in the treatment of several mental disorders. It is known for binding to various plasma proteins, including haemoglobin, to some extent.
2. Phenobarbital: Phenobarbital is a barbiturate used primarily to treat seizures. It is primarily bound to plasma proteins such as albumin rather than haemoglobin.
3. Phenothiazine: This is not a specific drug but a class of neuroleptic drugs that includes chlorpromazine. In general, drugs from this group are known to bind to various proteins, but the specific question refers to individual binding to haemoglobin, which is uncommon.
4. Phenytoin: Phenytoin is an anti-seizure medication. Similar to phenobarbital, it binds extensively to plasma proteins like albumin and does not bind to haemoglobin.

Based on the explanation above, Phenobarbital (B), Phenothiazine (C), and Phenytoin (D) are drugs that do not bind to haemoglobin. Therefore, the most appropriate answer to the question is:

1. B, C and D only