Question

The majority of drugs that least binded to antivascular tissue is

• A. Liver
• B. Muscle
• C. Lungs
• D. Kidneys

Answer 1

The Correct Option is B

To determine which drug binds the least to antivascular tissue, it's essential to understand the concept of drug distribution in the body. The binding of drugs to tissues, including vascular and non-vascular tissues, is influenced by several factors such as blood flow, tissue composition, and the physiochemical properties of the drug.

In this context, we are focusing on tissues such as the liver, muscle, lungs, and kidneys. The key is to identify tissues with less vascularity or lower capacity for drug binding.

Among the provided options:

• Liver: Highly vasculated and involved in metabolism, hence drugs often bind significantly here.
• Muscle: Less vasculated compared to the liver and kidneys, meaning it typically binds fewer drugs.
• Lungs: Highly vasculated due to the need for gas exchange and can bind certain drugs, especially those inhaled or related to bronchial action.
• Kidneys: Highly vasculated, crucial for excretion, filters blood, and binds significantly to drugs related to kidney processing.

The muscle tissue generally binds the least to antivascular tissues due to its lower blood flow compared to organs with a high metabolic rate and vascularity like the liver, lungs, and kidneys.

Therefore, the correct answer is:

• Muscle