Which among the following is not the process of drug degradation:

Question

cdquestions Admin · Accepted Answer

Step 1: Understanding drug degradation processes. Drug degradation refers to the chemical breakdown of pharmaceutical compounds, leading to loss of potency and stability. The major processes of drug degradation include:  - Photolysis: Breakdown of a drug due to exposure to light. - Decarboxylation: Loss of a carboxyl group ($-COOH$), leading to structural modifications.  - Hydrolysis: Reaction with water causing drug decomposition, common in esters and amides.  Step 2: Why hemolysis is incorrect. - Hemolysis refers to the breakdown of red blood cells (RBCs), releasing hemoglobin into the blood. It is a biological process, not related to drug degradation.  Step 3: Explanation of incorrect options. - (A) Photolysis, (B) Decarboxylation, and (D) Hydrolysis are all valid mechanisms of drug degradation.

Answer

<div>Photolysis <br></div>

Answer

Decarboxylation

Answer

<div>Hemolysis <br></div>

Answer

<div>Hydrolysis <br></div>

	Ingrediant		Function	Table A	Table B	Table C	Table D
A	Aceta- minophen	I	Drug	300 mg	-	300 mg	300 mg
B	Aspirin	II	Drug	-	300 mg	-	-
C	Lactose	III	Filler	100 mg	100 mg	-	100 mg
D	Avicel	IV	Filler	-	-	100 mg	-
	starch		Dis-integrant	50 mg	50 mg	-	50 mg
	Avicel		Dis-integrant	-	-	50 mg	-
	Magsterate		Lubricant	2 mg	2 mg	2 mg	2 mg
	Gelatin		Binder	10 mg	10 mg	10 mg	10 mg

List I		List II
A	Grignard reagent	I	R₂CuLi
B	Gilman reagent	II	RMgX
C	Benzyne mechanism	III	2 molecules of CH₃CHO
D	Aldol condensation	IV	S_NAr

Which among the following is not the process of drug degradation:

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The Correct Option is C

Solution and Explanation

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