Question:

Which of the following is the leading cause of chronic kidney disease worldwide?

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Control glycemic and blood pressure targets to prevent progression of diabetic nephropathy.
Updated On: Dec 26, 2025
  • Glomerulonephritis
  • Hypertension
  • Diabetes mellitus
  • Polycystic kidney disease
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The Correct Option is C

Solution and Explanation

Step 1: Understanding the question.
The question asks for the most common etiology of CKD globally in adults.
Step 2: Analyzing the options.
(A) Glomerulonephritis: More common in some developing regions but not globally leading.
(B) Hypertension: Second most common.
(C) Diabetes mellitus: Correct — Diabetic nephropathy is the leading cause worldwide due to rising diabetes prevalence.
(D) Polycystic kidney disease: Rare genetic cause.
Step 3: Conclusion.
The correct answer is (C) Diabetes mellitus, as it is the leading cause of chronic kidney disease worldwide.
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