Question:

What is the leading cause of chronic kidney disease worldwide as per recent global burden studies?

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Tight glycemic and blood pressure control are key to delaying diabetic nephropathy progression.
Updated On: Dec 26, 2025
  • Hypertension
  • Glomerulonephritis
  • Diabetes mellitus
  • Obstructive nephropathy
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The Correct Option is C

Solution and Explanation

Step 1: Understanding the question.
The question asks for the primary etiology of CKD globally, driven by metabolic factors.
Step 2: Analyzing the options.
(A) Hypertension: Major contributor but second to diabetes.
(B) Glomerulonephritis: More prevalent in some regions but not globally leading.
(C) Diabetes mellitus: Correct — High fasting glucose is the top risk factor per GBD studies.
(D) Obstructive nephropathy: Less common globally.
Step 3: Conclusion.
The correct answer is (C) Diabetes mellitus, the leading cause of chronic kidney disease worldwide.
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