Question

Which of the following is a water-soluble base?

• A. \( \text{Soft paraffin} \)
• B. \( \text{Hydroxyethylcellulose} \)
• C. \( \text{Cocoa butter} \)
• D. \( \text{Vaseline} \)

Hint:

Water-soluble bases enhance drug absorption by providing better solubility and stability in aqueous environments.

Answer 1

The Correct Option is B

Hydroxyethylcellulose is a water-soluble polymer used as a thickening agent and stabilizer in pharmaceutical formulations. Unlike soft paraffin, cocoa butter, and Vaseline, which are hydrophobic, hydroxyethylcellulose dissolves in water and forms gel-like structures. It improves viscosity and bioavailability in topical and oral drug formulations.