Question:

In LC-MS (Liquid Chromatography-Mass Spectrometry) instrument, the interface is applied between:

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In LC-MS, the interface links the liquid chromatography system and mass spectrometer for component analysis.
Updated On: Jun 12, 2025
  • Liquid chromatography and UV detector
  • Liquid chromatography and mass spectrometer
  • UV detector and mass spectrometer
  • None of the above
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The Correct Option is B

Solution and Explanation

In LC-MS, the interface connects the liquid chromatography (LC) system with the mass spectrometer (MS). The liquid chromatography separates the sample components, and the mass spectrometer detects them based on their mass-to-charge ratio. The interface between LC and MS is crucial for transferring the eluted compounds from the chromatographic column to the mass spectrometer for analysis. Thus, the correct answer is (b) Liquid chromatography and mass spectrometer.
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