Question

Over-expression of _________ in somatic cells leads to cell immortalization.

• A. \( \text{p53} \)
• B. \( \text{Cadherin} \)
• C. \( \text{Telomerase} \)
• D. \( \text{DNA ligase} \)

Hint:

Telomerase overexpression sustains indefinite cell division, a hallmark of cancer.

Answer 1

The Correct Option is C

Telomerase maintains telomere length, preventing cellular senescence and enabling uncontrolled division, a key feature in cancer cell immortalization.