Question

Which of the following enzymes plays a vital role in the pathogenesis of HIV infection?

• A. RNA polymerase
• B. RNA polymerase II
• C. Tag polymerase
• D. Reverse Transcriptase

Hint:

Reverse transcriptase is essential for HIV replication, converting viral RNA into DNA for integration into the host genome.

Answer 1

The Correct Option is D

Step 1: Understanding HIV Pathogenesis 
HIV uses reverse transcriptase to convert its RNA genome into DNA, which is then integrated into the host genome. 
Step 2: Evaluating the Options 
- RNA polymerase: Not involved in HIV pathogenesis. 
- RNA polymerase II: Involved in eukaryotic transcription but not in HIV replication. 
- Tag polymerase: Not related to HIV replication. 
- Reverse Transcriptase: Correct, HIV uses reverse transcriptase to replicate its RNA genome into DNA. 
Step 3: Conclusion 
Reverse transcriptase is a critical enzyme for the replication of HIV.