Question

Which of the following drug delivery systems comprises a hydrophobic core and a hydrophilic surface?

• A. \( \text{Liposomes} \)
• B. \( \text{Micelles} \)
• C. \( \text{Reverse micelles} \)
• D. \( \text{None of the above} \)

Hint:

Micelles improve drug solubility by encapsulating lipophilic molecules in their core while maintaining aqueous compatibility.

Answer 1

The Correct Option is B

Micelles consist of a hydrophobic core and a hydrophilic surface, enabling the solubilization of poorly water-soluble drugs. They form spontaneously in aqueous solutions when surfactants reach the critical micelle concentration (CMC). Micelles enhance drug absorption and protect sensitive drugs from degradation.