Question

When granules stick to the die, what may be a remedy?

• A. \( \text{External lubrication} \)
• B. \( \text{Drying of granules} \)
• C. \( \text{Decrease the dwell time} \)
• D. \( \text{Increase in binder quantity} \)

Hint:

Proper lubrication in tablet formulation minimizes defects and improves manufacturing efficiency.

Answer 1

The Correct Option is A

Granules sticking to the die cavity occurs due to high moisture content or inadequate lubrication. Applying external lubrication using magnesium stearate or talc prevents adhesion, ensuring smooth tablet compression. Other methods, such as granule drying, may also be beneficial.