The number of neutrons in an atom can be calculated using the formula:
\[
\text{Number of Neutrons} = \text{Mass Number} - \text{Atomic Number}
\]
Here, the atomic number is given as \( 35 \) and the mass number is given as \( 80 \). Substituting these values into the formula:
\[
\text{Number of Neutrons} = 80 - 35 = 45
\]
Thus, the correct answer is \( \boxed{45} \).