Question

What are chromosomal disorders? Describe Turner’s syndrome and Klinefelter’s syndrome.

Hint:

Turner’s syndrome primarily affects females with a single X chromosome (45, XO), whereas Klinefelter’s syndrome affects males with an extra X chromosome (47, XXY).

Answer 1

Overview of Chromosomal Disorders: Chromosomal disorders are genetic conditions that arise from anomalies in chromosome number or structure, resulting in various developmental and health issues. 
-Aneuploidy: An atypical number of chromosomes. 
-Structural alterations such as deletion, duplication, or translocation of chromosomal segments. 
Common Chromosomal Disorders: 
1. Turner’s Syndrome (45, XO): 
-Characterized by the loss of one X chromosome in females. 
-Features include short stature, webbed neck, and poorly developed ovaries. 
-Results in infertility, absence of secondary sexual traits, and possible cardiac issues. 
2. Klinefelter’s Syndrome (47, XXY): 
-Occurs in males due to an additional X chromosome. 
-Presents with tall stature, sparse body hair, gynecomastia, and small testes. 
-Typically causes decreased fertility and some cognitive challenges.