Question

True about type 1 diabetes mellitus:

• A. Decreased protein catabolism
• B. Decreased hepatic Glucose output
• C. Increased lipolysis
• D. Increase glucose uptake

Answer 1

The Correct Option is C

In type 1 diabetes mellitus, several metabolic changes occur due to the absence of insulin. Insulin is an anabolic hormone responsible for promoting glucose uptake into tissues, inhibiting glucose production by the liver, increasing protein synthesis, and reducing lipolysis.

Here is why each option is correct or incorrect:

• Decreased protein catabolism: This is incorrect. In type 1 diabetes, there is increased protein catabolism due to the lack of insulin, leading to muscle wasting.
• Decreased hepatic glucose output: This is incorrect. In type 1 diabetes, due to insulin deficiency, hepatic glucose output is increased.
• Increased lipolysis: This is correct. The deficiency of insulin leads to increased lipolysis, resulting in the release of free fatty acids into the bloodstream.
• Increase glucose uptake: This is incorrect. Due to the absence of insulin, there is a decrease in glucose uptake by muscle and adipose tissues.

Therefore, the correct statement about type 1 diabetes mellitus is increased lipolysis.