Question:

The type of linkage present between nucleotides is :

Updated On: Apr 9, 2025
  • Phosphoester linkage
  • Phosphodiester linkage
  • Amide linkage
  • Glycosidic linkage
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The Correct Option is B

Approach Solution - 1

  • In nucleic acids like DNA and RNA, the nucleotides are linked together by phosphodiester linkages. This bond forms between the phosphate group of one nucleotide and the sugar (deoxyribose or ribose) of the next nucleotide.
  • The phosphodiester bond involves a phosphate group linking the 3' carbon atom of one sugar molecule to the 5' carbon atom of another sugar molecule.

Thus, the type of linkage present between nucleotides is phosphodiester linkage, making option (B) the correct answer.

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Approach Solution -2

In nucleic acids, nucleotides are joined together by phosphodiester linkages. This type of linkage involves a phosphate group that connects the 3' carbon of one nucleotide's sugar to the 5' carbon of the next nucleotide's sugar. The phosphodiester bond forms the backbone of DNA and RNA. It allows for the formation of long chains of nucleotides, which ultimately make up the genetic material.  

  • Phosphoester linkages occur in ester bonds involving phosphoric acid but are not the main type of bond in nucleic acids.  
  • Amide linkage occurs in proteins (in peptide bonds), not in nucleic acids.  
  • Glycosidic linkages connect sugars to other molecules but are not the bonds between nucleotides.
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