Question

The mode of action of nerve gas is:

• A. Inhibition of acetylcholinesterase
• B. Blockade of sodium channels
• C. Inhibition of gamma-aminobutyric acid (GABA)
• D. Activation of muscarinic receptors

Hint:

Nerve gases inhibit acetylcholinesterase, causing continuous neurotransmission and overstimulation.

Answer 1

The Correct Option is A

Nerve gases, such as Sarin and VX, inhibit acetylcholinesterase, the enzyme responsible for breaking down acetylcholine in synaptic clefts. This results in continuous stimulation of muscles and glands, leading to overstimulation and paralysis. The other options are incorrect because nerve gases specifically inhibit acetylcholinesterase, not sodium channels, GABA, or muscarinic receptors. Thus, the correct answer is (a) Inhibition of acetylcholinesterase.