Question

Drugs used for peptic ulcer like cimetidine, ranitidine, famotidine, nizatidine belong to which category?

• A. Antacids
• B. Proton pump blockers/inhibitors
• C. H2 antagonists/receptor blockers
• D. Prostaglandin (PG) analogues
• E.

Hint:

H2 receptor antagonists reduce stomach acid production and are commonly used in peptic ulcer treatment.

Answer 1

The Correct Option is C

Step 1: Understanding H2 antagonists.
Cimetidine, ranitidine, famotidine, and nizatidine are all H2 receptor antagonists, which work by blocking histamine receptors in the stomach lining, thus reducing stomach acid production.
Step 2: Analyzing the options.
- (1) Antacids: Incorrect. Antacids neutralize stomach acid but are not the same as H2 antagonists.
- (2) Proton pump blockers/inhibitors: Incorrect. Proton pump inhibitors like omeprazole work by inhibiting the proton pumps in the stomach.
- (3) H2 antagonists/receptor blockers: Correct. These drugs inhibit the histamine receptors in the stomach, reducing gastric acid secretion.
- (4) Prostaglandin (PG) analogues: Incorrect. PG analogues protect the stomach lining but do not directly reduce acid production.
Step 3: Conclusion.
Therefore, the correct answer is (3), as these drugs are classified as H2 receptor blockers.