Question:

The disease Itai-Itai is caused by contamination of drinking water with which of the following?

Updated On: Mar 28, 2025
  • Mercury
  • Cadmium
  • Arsenic
  • Chromium
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The Correct Option is B

Solution and Explanation

The disease "Itai-Itai" is caused by contamination of drinking water with Cadmium.

Additional Context:

  • About Itai-Itai disease:
    • First recognized in Japan's Toyama Prefecture (1910s-1940s)
    • Name translates to "it hurts-it hurts" due to severe bone pain
    • Caused by chronic cadmium poisoning from contaminated Jinzu River
  • Health effects:
    • Renal tubular dysfunction leading to proteinuria
    • Osteomalacia (bone softening) and osteoporosis
    • Extreme bone fragility and multiple fractures
  • Source of contamination:
    • Mining operations releasing cadmium into water systems
    • Bioaccumulation in rice crops irrigated with contaminated water
  • Other heavy metal diseases:
    • Mercury: Minamata disease (neurological damage)
    • Arsenic: Blackfoot disease (peripheral vascular disease)
    • Chromium: Lung cancer and dermatitis (occupational hazards)
  • Prevention:
    • Modern mining wastewater treatment
    • Soil remediation techniques
    • WHO guideline: <3 µg/L cadmium in drinking water

Correct Answer: (2) Cadmium.

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