Question

The Cri-du-chat syndrome, a chromosomal aberration occurs in humans due to ...........

• A. Duplication
• B. Inversion
• C. Deletion
• D. Translocation

Hint:

Cri-du-chat syndrome is caused by a deletion in chromosome 5, leading to developmental issues and distinct physical features.

Answer 1

The Correct Option is C

Step 1: Understanding Cri-du-chat syndrome.
Cri-du-chat syndrome is caused by a deletion in the short arm of chromosome 5. The name "Cri-du-chat" comes from the characteristic cry of affected infants, which sounds like a cat's meow.
Step 2: Analyzing the options.
- Duplication refers to the repetition of a part of the chromosome. This is not the cause of Cri-du-chat syndrome.
- Inversion involves a part of the chromosome being reversed. This is also not the cause.
- Deletion is the correct answer, as Cri-du-chat syndrome occurs due to the loss of a portion of chromosome 5.
- Translocation involves the transfer of a part of one chromosome to another, which does not cause Cri-du-chat syndrome.
Step 3: Conclusion.
The correct answer is (3) Deletion.
Final Answer: \[ \boxed{\text{The correct answer is (3) Deletion.}} \]