Question

Study the following regarding genetic disorders and identify the correct statements.
I) Cystic fibrosis follows an autosomal dominant inheritance pattern.
II) Thalassemia is caused by mutation affecting haemoglobin synthesis
III) Sickle cell anaemia results from a point mutation in the β-globin gene.
IV) Phenylketonuria (PKU) is an X-linked recessive disorder.
 

• A. I and II
• B. II and III
• C. I and IV
• D. II and IV

Hint:

Remember: CF and PKU are autosomal recessive; sickle cell and thalassemia affect hemoglobin genes.

Answer 1

The Correct Option is B

Thalassemia is caused by mutation in genes involved in haemoglobin synthesis.
Sickle cell anemia is due to point mutation in the β-globin gene.
Cystic fibrosis is actually autosomal recessive, not dominant.
Phenylketonuria is autosomal recessive, not X-linked.