Question:
Single base difference in ApoE gene is associated with:
Single base difference in ApoE gene is associated with:
Updated On: Jul 5, 2025
- Resistance to HIV (Human Immunodeficiency Virus)
- Migraine
- Huntington disease
- Alzheimer’s disease
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The Correct Option is D
Solution and Explanation
The ApoE gene encodes apolipoprotein E, which plays a crucial role in lipid metabolism. A single base polymorphism in the ApoE gene, particularly the ApoE4 allele, is strongly associated with an increased risk of Alzheimer’s disease.
- Option D: Correct. ApoE4 allele increases susceptibility to Alzheimer’s disease.
- Option A, B, C: Incorrect. These conditions are linked to other genes or factors, not the ApoE gene.
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