Question:

Severe combined immunodeficiency disease is caused due to the absence of:

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Always remember the deficiency of important enzymes and its relation to certain diseases.
Updated On: Feb 19, 2025
  • Adenosine diphosphate
  • Adenosine deaminase
  • Adenosine cyclase
  • Guanidine nitrate
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The Correct Option is B

Solution and Explanation

Adenosine deaminase (ADA): Severe combined immunodeficiency (SCID) is a genetic disorder caused by the deficiency of the enzyme adenosine deaminase (ADA). This enzyme is essential for the normal development and function of the immune system, especially T and B lymphocytes. Its absence causes the buildup of toxic metabolites that damage these cells and the immune response is diminished. Adenosine diphosphate: ADP is a nucleotide involved in cellular processes. Adenosine cyclase: This is an enzyme that is involved in cyclic AMP formation. Guanidine nitrate: This is a compound that has no connection with SCID.
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