Question

Severe combined immunodeficiency disease is caused due to the absence of:

• A. Adenosine diphosphate
• B. Adenosine deaminase
• C. Adenosine cyclase
• D. Guanidine nitrate

Hint:

Always remember the deficiency of important enzymes and its relation to certain diseases.

Answer 1

The Correct Option is B

Adenosine deaminase (ADA): Severe combined immunodeficiency (SCID) is a genetic disorder caused by the deficiency of the enzyme adenosine deaminase (ADA). This enzyme is essential for the normal development and function of the immune system, especially T and B lymphocytes. Its absence causes the buildup of toxic metabolites that damage these cells and the immune response is diminished. Adenosine diphosphate: ADP is a nucleotide involved in cellular processes. Adenosine cyclase: This is an enzyme that is involved in cyclic AMP formation. Guanidine nitrate: This is a compound that has no connection with SCID.