Question

Select the drug indicated for extended drug resistance tuberculosis (XDR TB).

• A. \( \text{Linezolid} \)
• B. \( \text{Moxifloxacin} \)
• C. \( \text{Tyrocidin} \)
• D. \( \text{Azithromycin} \)

Hint:

Effective treatment of XDR-TB involves a combination of antibiotics tailored to resistance patterns.

Answer 1

The Correct Option is A

Linezolid is an oxazolidinone antibiotic recommended for XDR-TB, particularly for cases resistant to multiple first-line drugs. It inhibits bacterial protein synthesis by binding to the 50S ribosomal subunit, preventing infection spread. Other drugs listed have different antibacterial spectrums, with limited efficacy against XDR-TB.