Question

Remdesivir interferes with the action of which viral enzyme?

• A. \( \text{RNA-dependent RNA polymerase} \)
• B. \( \text{Exoribonuclease} \)
• C. \( \text{DNA-dependent RNA polymerase} \)
• D. \( \text{DNA gyrase} \)

Hint:

RdRp inhibitors are effective against RNA viruses and play a crucial role in antiviral therapy by blocking viral genome replication.

Answer 1

The Correct Option is A

Remdesivir is a nucleotide analog prodrug that inhibits viral RNA-dependent RNA polymerase (RdRp). It gets incorporated into viral RNA during replication, leading to premature chain termination. This action disrupts the replication process of viruses like SARS-CoV-2, making remdesivir an antiviral treatment option.