Question

Phototoxicity is shown by all EXCEPT:

• A. \( \text{Doxycycline} \)
• B. \( \text{Chlorpromazine} \)
• C. \( \text{Thiazide and quinolones} \)
• D. \( \text{Rosiglitazone} \)

Hint:

Phototoxic drugs trigger skin reactions upon UV exposure; protective measures are advised.

Answer 1

The Correct Option is D

Phototoxicity occurs when drugs absorb UV light, generating reactive oxygen species, leading to skin damage. Doxycycline, chlorpromazine, and quinolones show significant phototoxic effects, while rosiglitazone, an antidiabetic drug, does not. Patients on phototoxic drugs should avoid excessive sun exposure.